Pancreatic Adenocarcinoma: An Analysis of Drug Therapy Options through Interaction Maps and Graph Theory
Summary
Pancreatic cancer is the fourth leading cause of cancer-related deaths in humans (ASCO 2012). Pancreatic cancer cells exhibit a different gene expression profile from normal cells, with approximately 122 over-expressed proteins. A novel method was created to find the most important areas for future drug development based on influential disease-causing proteins in pancreatic cancer that currently lack drug treatments.
Anvita Gupta, Sejal Aggarwal, Sangeeta Agrawal
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